Clinical uses of fluorescein in medical practice: literature review
DOI:
https://doi.org/10.37497/ijhmreview.v8i1.314Keywords:
Fluorescein, Neurosurgery, Angiography and OphthalmologyAbstract
Background: Sodium fluorescein (FS) is a dye, of the xanthene type, used in the surgical field both for ophthalmological procedures; in the latter, currently a barrier applied to the delimitation of hematomas in a BHE case (the latter for different types of hematomas in a BHE case, such as the different types of hematomas, such as the various types of hematomas.
Aim: To review the literature regarding the clinical uses of fluorescein in medical practice.
Method: The bibliographic databases were Scielo and Lilacs, and the search used the Publish or Perish tool.
Results: The use of fluorescein-only rupture was effective in the process of total tumor resection (GTR) of severe tumors with a good margin of safety and high specificity, due to its potential for accumulation in the regions of BBB resection and accurately delineating the tumor region.
Conclusion: The use of sodium fluorescein can be used both in ophthalmology and neurosurgery.
References
ACERBI, Francesco; BROGGI, Morgan; SCHEBESCH, Karl-Michael; et al. Fluorescein-Guided Surgery for Resection of High-Grade Gliomas: A Multicentric Prospective Phase II Study (FLUOGLIO). Clinical Cancer Research, v. 24, n. 1, p. 52–61, 2017.
BURGESS, Kevin; UENO, Yuichiro; JIAO, Guan-Sheng. Preparation of 5-and 6- Carboxyfluorescein. Synthesis, v. 2004, n. 15, p. 2591–2593, 2004.
DA SILVA, Vinicius; DA SILVA, Jefferson; DA SILVA, Carlos. Skull Base Meningi- omas and Cranial Nerves Contrast Using Sodium Fluorescein: A New Application of an Old Tool. Journal of Neurological Surgery Part B: Skull Base, v. 75, n. 04, p. 255–260, 2014.
OKUDA, Takeshi; KATAOKA, Kazuo; YABUUCHI, Tomonari; et al. Fluorescence- guided surgery of metastatic brain tumors using fluorescein sodium. Journal of Clinical Neuroscience, v. 17, n. 1, p. 118–121, 2010.
SCHEBESCH, Karl-michael; BRAWANSKI, Alexander; HOHENBERGER, Christoph; et al. Fluorescein sodium-guided surgery of malignant brain tumors: history, current concepts, and future projects. Turkish Neurosurgery, v. 26, n. 2, p. 185-194, 2016.
SCHWAKE, Michael; STUMMER, Walter; SUERO MOLINA, Eric Jose; et al. Simul- taneous fluorescein sodium and 5-ALA in fluorescence-guided glioma surgery. Acta Neurochirurgica, v. 157, n. 5, p. 877–879, 2015.
SUN, Wei-Chuan; GEE, Kyle R.; KLAUBERT, Dieter H.; et al. Synthesis of Fluorinated Fluoresceins. The Journal of Organic Chemistry, v. 62, n. 19, p. 6469–6475, 1997.
TABAEE, Abtin; PLACANTONAKIS, Dimitris G.; SCHWARTZ, Theodore H.; et al. Intrathecal Fluorescein in Endoscopic Skull Base Surgery. Otolaryngology–Head and Neck Surgery, v. 137, n. 2, p. 316–320, 2007.
XIANG, Yan; ZHU, Xiao-Peng; ZHAO, Jian-Nong; et al. Blood-Brain Barrier Disruption, Sodium Fluorescein, And Fluorescence-Guided Surgery of Gliomas. British Journal of Neurosurgery, v. 32, n. 2, p. 141–148, 2018.
XIAO, Shi-yin; ZHANG, Ji; ZHU, Zheng-quan; et al. Application of fluorescein sodium in breast cancer brain-metastasis surgery. Cancer Management and Research, v. Volume 10, p. 4325–4331, 2018.
Downloads
Published
How to Cite
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
Authors who publish in this journal agree to the following terms: The author(s) authorize the publication of the text in the journal; The author(s) guarantee that the contribution is original and unpublished and is not in the process of being evaluated by any other journal(s); The journal is not responsible for the opinions, ideas, and concepts contained in the texts, as these are the sole responsibility of their respective author(s); The editors reserve the right to make adjustments to the text in order to ensure that it adheres to the standards of the journal. Authors retain the copyrights and grant the journal the right of first publication, with the article simultaneously licensed under the Creative Commons Attribution License which allows the sharing of the article with the acknowledgment of authorship and initial publication in this journal. Authors are authorized to take additional contracts separately, for the non-exclusive distribution of the version of the article published in this journal (e.g. publication in an institutional repository or as a book chapter), with the acknowledgment of authorship and initial publication in this journal.
Authors are allowed and encouraged to publish and distribute their work online (e.g. in institutional repositories or on their personal webpage) at any point before or during the editorial process, as this can generate productive changes as well as increase the impact and citation of published work (See The Effect of Free Access at http://opcit.eprints.org/oacitation-biblio.html)
